SAT-492 Impending Thyroid Storm Induced by Checkpoint Inhibitors
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چکیده
منابع مشابه
Impending thyroid storm in a pregnant woman with undiagnosed hyperthyroidism
RATIONALE Thyroid storm is a rare complication during caesarean section of patients with hyperthyroidism. It occurs abruptly, with a high mortality rate if not recognized immediately and aggressively treated. Herein, we reported a case of impending thyroid storm during a caesarean section. PATIENT CONCERNS A healthy 23-year-old woman with undiagnosed hyperthyroidism underwent an emergency cae...
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CONTEXT In recent years, progress has been made in cancer immunotherapy by the development of drugs acting as modulators of immune checkpoint proteins, such as the cytotoxic T-lymphocyte antigen-4 (CTLA4) and programmed death-1 (PD-1), two co-inhibitory receptors that are expressed on T cells upon activation. These molecules play crucial roles in maintaining immune homeostasis by down-regulatin...
متن کاملThyroid Storm Precipitated by Duodenal Ulcer Perforation
Thyroid storm is a rare and life-threatening complication of thyrotoxicosis that requires prompt treatment. Thyroid storm is also known to be associated with precipitating events. The simultaneous treatment of thyroid storm and its precipitant, when they are recognized, in a patient is recommended; otherwise such disorders, including thyroid storm, can exacerbate each other. Here we report the ...
متن کاملThyroid storm precipitated by acute biliary pancreatitis
Thyroid storm or thyroid crisis is an acute, life-threatening exacerbation and sudden releasing large amounts of thyroid hormone in a short period of time. Only 1%–2% of people with hyperthyroidism will develop thyroid storm[1]. Thyroidectomy was formerly the most common cause of thyroid crisis. Nowadays post thyroidectomy crisis is an uncommon incidence, because of preoperative testing and ear...
متن کاملThyrotoxicosis and thyroid storm.
Thyroid storm represents the extreme manifestation of thyrotoxicosis as a true endocrine emergency. Although Grave's disease is the most common underlying disorder in thyroid storm, there is usually a precipitating event or condition that transform the patient into life-threatening thyrotoxicosis. Treatment of thyroid storm involves decreasing new hormone synthesis, inhibiting the release of th...
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ژورنال
عنوان ژورنال: Journal of the Endocrine Society
سال: 2020
ISSN: 2472-1972
DOI: 10.1210/jendso/bvaa046.1149